Molecular Biophysics (Jan Lipfert)
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Welcome to the Lipfert Lab!

We are fascinated by how biological macromolecules (DNA, RNA, and proteins) adopt their three-dimensional shapes, make specific interactions, can deform under external forces and torques, and undergo conformational transitions to carry out the biological functions they have evolved to do. We use a range of biophysical tools, in particular single-molecule magnetic tweezers and solution X-ray scattering, to provide insights into the structure and mechanisms of these biological machines.

Our lab is part of the Chair for Biophysics and Molecular Materials headed by Hermann Gaub in the Physics Department of the LMU Munich. We are affiliated with the Nanosystem Initiative Munich (NIM), which is one of the Clusters of Excellence selected in the first round of Germany's Excellence Initiative, and with the Center for NanoScience (CeNS). Physically, we are located at the main LMU campus in Munich (see CONTACT for our shipping address and directions).